Yee Man Yuen
Earley,Berkshire
Overview
27
27
years of professional experience
Work history
Clinical Development Risk and Compliance Manager
Parexel International
Remote, United Kingdom
2025.07 - Current
Project Quality & Risk Manager
Parexel International
Hong Kong, China
2021.03 - 2025.06
- Change in job title from Project Quality & Risk Manager to Clinical Development Risk and Compliance Manager
- Current job duties remain the same as the current role
Senior Clinical Operations Leader
Parexel International
Hong Kong, China
2018.03 - 2021.02
- Provided leadership and direction to project team members daily.
- Contributed to project tools and project plan central file maintenance.
- Developed site selection and monitoring plan for project team execution.
- Reviewed patient recruitment and retention plans to maintain feasibility.
- Evaluated resourcing needs and monitored them through project lifecycle.
- Managed study start-up activities across assigned sites and functions.
- Provided performance feedback to team members as required.
- Addressed and escalated site issues, then drove them to closure.
- Monitored study timelines, patient recruitment, retention, and data cleaning.
- Oversaw maintenance and quality checks for central project files.
- Ensured structured handover between project team members during transitions.
- Implemented process improvements to strengthen project delivery and controls.
- Attended client investigator and team meetings to share updates.
- Prepared for and followed up on audits and inspections.
- Acted as Project Leader for projects involving a small number of services, where no Project Leader is assigned.
Senior Clinical Operations Leader
Parexel International
Hong Kong, China
2011.05 - 2015.07
- Provide leadership and direction to project team members
- Provide input to project tools, PL project plan, Central File Maintenance Plan
- Develop site selection and monitoring plan for the team
- Review and provide input into patient recruitment plan and retention plan
- Evaluate and identify resourcing needs and continuously monitor over life cycle of large/complex project and/or program
- Manage study start-up activities
- Early recognition of areas of potential problems and provide input to contingency plans
- Monitor study timelines, patient recruitment, retention and data cleaning to ensure successful outcome of the project and/or program.
- Oversee maintenance and quality check of Central Files
- Identify changes in scope and liaise with Project Leader
- Participate in client, investigator and team meetings
- Prepare, participate in and follow up on audits / inspections
- Responsible for coordinating the functional team members and their activities across all geographies, liaising with project management and the sponsor to ensure that the Global Clinical Operations deliverables are met in time within the budget and at a high quality.
- Accountability for the execution of the clinical operations strategy and plan within the project, and can competently and independently lead large, complex projects and/or programs.
Clinical Operations Lead/ Senior Clinical Research
Pfizer Corporation Hong Kong Limited, Hong Kong
Hong Kong, China
2007.10 - 2011.05
- Coordinates the clinical activities on international multi centre trials
- Implement strategies to ensure timely subject recruitment
- Support the Project Management
- Evaluate and identifying resourcing needs
- Ensure that timeline, quality and productivity of the project are met
- Participates in the organization of client, investigator and team meetings
- Recognizes any potential problems and formulates suitable contingency plans
- Mentorship to junior Clinical Research Associate
- Involved in the feasibility, site selection, pre-study visits at site
- Collect the documentation for regulatory/EC approvals
- Conduct all the kind of visit at site - initiation, monitoring, closure
- Maintain up to date the Files in house and on site
- Collaborates with other departments for safety information reporting
- Responsible for source data verification and Case Report Forms collection
- Responsible for data queries management, study progress reporting and quality control check of the files
- Attends all study related meetings and conference calls
Research Assistant
University of Hong Kong
Hong Kong, China
2005.10 - 2006.09
- Responsible for assisting in vivo, in vitro and clinical research about renal diseases.
Teaching assistant
The Chinese University of Hong Kong
Hong Kong, China
2004.09 - 2005.06
- Prepared classroom materials to facilitate efficient lessons.
Laboratory technician
Po Leung Kuk Centenary L.S. Chung Memorial College
Hong Kong, China
1999.09 - 2003.07
- Prepare materials for student's laboratory section
Education
Certificate of Higher Education - Pharmacology and Pharmaceutical Management
HKU SPACE
Hong Kong /2010 -
Master of Philosophy - Bioochemistry
The Chinese University of Hong Kong
Hong Kong /2005 -
Bachelor of Science - Food and Nutritional Sciences
The Chinese University of Hong Kong
Hong Kong /2003 -
Skills
A team-oriented Clinical Development Risk and Compliance Manager with a strong research background with 17 years of experience in the clinical research industry
Serve as primary project quality expert, point of contact and support to project team leadership throughout the project Manage the Quality Risk Evaluation (QRE) workflow and communicate results to the project team (PL, FLs) Provide support with quality issue management, audits and inspections and project quality and risk consultancy as required Assess operational execution using a risk-based approach to verify adherence to standards and assist with remediation when required and facilitate quality related interactions with clients
Language skills:
- Cantonese: Native speaker
- Mandarin: Fluent
- English: Fluent
Publications
- Yuen YM, Leung LK. (2007) Genistein and daidzein induced ApoA-1 transactivation in HepG2 cells expressing estrogen receptor a. British Journal of Nutrition. May;99(5):1007-12.
- Leung LK , Yuen YM, Leung HY, Wang Y. (2005) Dietary soya isoflavones and breast carcinogenesis: a perspective from a cell-culture model. Nutrition Research Review. 18:202-211.
- LK Leung, LS Po, TY Lau and YM Yuen. (2004). Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction. British Journal of Nutrition; 91, 831-839.
Timeline
Clinical Development Risk and Compliance Manager
Parexel International
2025.07 - Current
Project Quality & Risk Manager
Parexel International
2021.03 - 2025.06
Senior Clinical Operations Leader
Parexel International
2018.03 - 2021.02
Senior Clinical Operations Leader
Parexel International
2011.05 - 2015.07
Clinical Operations Lead/ Senior Clinical Research
Pfizer Corporation Hong Kong Limited, Hong Kong
2007.10 - 2011.05
Research Assistant
University of Hong Kong
2005.10 - 2006.09
Teaching assistant
The Chinese University of Hong Kong
2004.09 - 2005.06
Laboratory technician
Po Leung Kuk Centenary L.S. Chung Memorial College
1999.09 - 2003.07
Bachelor of Science - Food and Nutritional Sciences
The Chinese University of Hong Kong
/2003 -
Master of Philosophy - Bioochemistry
The Chinese University of Hong Kong
/2005 -
Certificate of Higher Education - Pharmacology and Pharmaceutical Management
HKU SPACE
/2010 -