Sofia Petrusenko

Conducted research on the role of stress-induced protein phosphorylation in Saccharomyces cerevisiae, focusing on how this process affects and promotes longevity. Employed statistical software tools, including R and Python, for data analysis to identify significant patterns and correlations between protein phosphorylation and yeast lifespan. Collaborated with a team of researchers to design experiments and discuss findings, contributing to the development of experimental protocols and research presentations. Presented findings in team meetings and contributed to the drafting of a paper outlining the research results, emphasizing the implications for understanding aging mechanisms.

Researched molecular mechanisms of aging contributing to neurodegeneration and retinal diseases, with a focus on proteostasis. Developed potential therapeutic approaches for conditions like Parkinson's disease, diabetic retinopathy, and age-related macular degeneration in collaboration with clinicians. Utilized cellular models (yeast to human cells) and brain/retinal organoids for experimental studies.

Investigated mechanisms of autophagy signalling and how these are compromised during ageing and the development of cancer, neurodegenerative disease and diabetes. Other areas of interest include autophagy in immunity and pathogenic infections, including coronaviruses (SARS and SARS-CoV2

Conducted a research on collective animal behaviour, exploring how social influence shapes biological processes. Investigated the evolution and organization of coordinated actions across different scales, from cells to animals and human societies. Combined experimental and theoretical approaches to uncover the principles governing group dynamics and social interactions.

Experimental study of DNA Hydration by novel approach - Pressure Perturbation Scanning Microcalorimetry