Passionate Clinical Pharmacology graduate with a commendation for academic excellence and a strong desire to contribute to the field of healthcare and pharmaceutical research. Eager to embark on a dynamic career journey as a Clinical Research Associate (CRA) or any other job related to clinical research to apply my theoretical knowledge and gain practical experience in the development of life-changing therapies.
performed the literature review for many articles related to antibiotic resistance microorganisms
The study was conducted to evaluate the aphrodisiac activity of oysters (Crassostrea madrasensis) in male Wistar rats. In the study, animals were divided into four groups with 6 animals in each, and oral administration of oyster extract was given to the test group, Sildenafil citrate for the standard group and distilled water for the control group respectively for 21 days. Sexual behavioral parameters (mounting and intromission frequencies, mounting, intromission, and ejaculatory latencies, post-ejaculatory interval, Copulatory rate, and index of libido) were observed. Serum testosterone and cholesterol concentrations, sperm count, and weight of sexual organs were also monitored.
Primary astrocyte cultures were prepared from P3 neonatal rat pups. Cultures were maintained for 21 days before being used for treatment. Treatments included cocktails of IL-6 with either IL-1α, TNFα, or both, and TLQP-21. Live images were captured before fixation after 16 or 24 hours, using phase contrast microscopy. Cultures were then stained with antibodies targeting GFAP (astrocyte pan marker) and AQP4 (astrocyte activation marker) before staining with Hoechst. These were then visualised using fluorescence microscopy. Morphological characteristics like vacuolation and hypertrophy were quantified between treatment groups. Finally, the Greiss assay was performed to evaluate the concentration of nitrite and nitrate in the cell culture media.