Nancy Henderson
Oxford,Oxfordshire
Summary
Master's graduate in Biomedical Sciences with strong research experience in inflammation, cell death pathways and molecular immunology. Skilled in tissue culture, protein analysis, and immunoassays, with an ongoing interest in translational cancer biology. Proven ability to mangage independent research projects and collaberate effectively across mulidisciplinary teams. Eager to contribute to innovative, patient-centered cancer research at the University of Oxford.
Overview
1
1
year of professional experience
4
4
years of post-secondary education
Work history
Master's Project
University of Manchester
Manchester
10.2023 - 04.2024
University of Manchester | Supervisor: Dr. Gloria Lopez-Castejon
Project: "Gliotoxin Induces Ferroptosis Hallmarks in an Uncharacterised Form of Macrophage Cell Death"
- Investigated non-apoptotic cell death pathways (notably ferroptosis) in macrophages exposed to gliotoxin, a fungal toxin.
- Cultured and treated THP1 and iBMDM cell lines; assessed cell death using WST-8, LDH, caspase activity, and GSH assays.
- Found disruptions in the GSH/GPX4 axis indicative of ferroptosis not reversed by LIP-1, suggesting hybrid cell death mechanisms.
- Wrote a 25-page dissertation; presented findings in internal poster sessions.
- Carried out day-to-day lab duties accurately and efficiently following Good Laboratory Practice.
MSci Experimental Skills Module
University of Manchester
Manchester
03.2023 - 03.2023
- Group project exploring 2R,6R-Hydronorketamine's effects on gamma oscillations in murine hippocampal and PFC brain slices.
- Performed microelectrode insertions and used Spike2 for oscillatory analysis.
- Challenged assumptions about HNK’s anticonvulsant properties in vitro.
Education
Master of Science - Biomedical Sciences MSci
University of Manchester
Manchester 09.2020 - 06.2024
Laboratory and Technical Skills
Molecular & Cellular Techniques: Western blotting, ELISA (IL-1β, IL-18), PCR, GSH & caspase assays, LDH viability assays
Cell Culture: THP1 and iBMDM macrophage lines; aseptic technique, enzymatic passaging, hemocytometer-based counting
Software: GraphPad Prism, Spike2, Microsoft Office, basic bioinformatics tools (NCBI, protein databases)
Data & Communication: Scientific writing (research reports, literature reviews), poster presentations, oral communication in lab/journal clubs
Additional Qualifications
Cheney School – Oxford, Oxfordshire
A-Levels, 2018–2020
- Biology (A*), Chemistry (A*), Geography (A*), Mathematics (A)
GCSEs, 2015-2018
- French (A*), Geography (A*), History (A*), Religious Education (A*)
- Biology (9), Chemistry (9), English Language (9), English Literature (9), Mathematics (8), Physics (9)
- NCFE Level 2 Certificate in Music Technology (Distinction)
References
References available upon request.
Timeline
Master's Project
University of Manchester
10.2023 - 04.2024
MSci Experimental Skills Module
University of Manchester
03.2023 - 03.2023
Master of Science - Biomedical Sciences MSci
University of Manchester
09.2020 - 06.2024
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