Nadine Abdullah
Belfast
Summary
Accomplished clinical research professional with extensive expertise in clinical trials management and a strong focus on patient safety and study protocol compliance. Demonstrates proficiency in MHRA regulations, pharmacovigilance, and ethical oversight, ensuring rigorous adherence to regulatory standards. Skilled in data analysis, risk assessment, and effective communication, facilitating seamless team collaboration and decision-making processes. Adept at managing early phase trials and first-in-human studies, with a proven track record of successful REC submissions and regulatory submissions. Committed to advancing clinical research through evidence-based practices and continuous professional development.
Overview
12
12
years of professional experience
4040
4040
years of post-secondary education
Work history
Principal Investigator
Celerion GB ltd
Belfast
05.2021 - 11.2025
- Principal investigator in phase I clinical trials
- Responsible for safety of subjects who participate in clinical trials and for executing study according to Research Ethics Committee/MHRA approved protocol and applicable FDA and GCP regulations
- Duties: Pre-Study: Review protocol and Investigator Brochure for subject safety, scientific, and operational feasibility of study
- Provide input to sponsor as indicated
- Prepare research ethics committee (REC) submission and review informed consent forms of volunteers
- Communicate with REC during protocol approval process and subject safety issues
- Explain study to participant and answer questions, ensure proper consent, and perform screening physical examination
- Final review of all screening data, ECGs, medical history and lab work prior to authorization of subjects' enrolment into studies
- During/Post Study: Review pre-dose lab work, ECGs, and other study data and determine appropriate action plan based on these results
- Perform physical examinations scheduled per protocol and unscheduled per adverse event during study conduct
- Manage adverse events/clinical evaluation of subjects and determine adverse event relationship to investigational product, severity, and etiology
- Review safety data with sponsors
- Compose serious adverse events (SAE) and other reporting documents as indicated
- Report all serious adverse events and (suspected unexpected serious adverse reactions) to sponsors and REC within statutory timelines
- Data review of all end-of-study data to determine if re-checks are necessary
- Safety monitoring – perform end-of-study physical exams and follow-up ongoing adverse events
- Case Report Forms review – review and sign all case report forms at end of study
- Assist in on-site client review of case report forms
- Inform REC of study completion
- Implemented best health and safety practices to ensure secure working environment.
- Maximized lab productivity by efficiently scheduling resources and equipment use.
- Facilitated knowledge transfer through regular team meetings and briefings.
- Prepared thorough, accurate case files to support investigations and facilitate arrests.
Clinical Research Physician
Medinova Warwickshire Quality Research Site
Warwickshire
10.2019 - 05.2021
- Sub-Investigator for Phase III clinical trials in diverse therapeutic areas:
- Pain management (osteoarthritis)
- Women's health (menopause, vasomotor symptoms, urinary incontinence)
- Dermatology (atopic dermatitis)
- Rheumatology (rheumatoid arthritis, osteoarthritis)
- Respiratory (asthma, chronic cough)
- Psychological stress/modulation.
- Responsibilities included subject recruitment, patient follow-up, adverse event monitoring (AEs/SAEs), regulatory compliance, monitoring visits, and patient-reported outcome tracking.
Medical Practitioner
Dr. Aly M. ABDELKARIM Urology Clinic
02.2019 - 10.2019
- Managing out-patient clinic
- Attending surgeries list as an observer
House Officer
Maldives Ministry of Health
09.2017 - 09.2018
- Managed out-patient cases and admitted unstable patients requiring further investigations.
- Coordinated referrals of emergency cases to main central hospital for urgent consultations.
- Clerked admitted patients, verifying medications and adjusting dosages as necessary.
- Executed mild to moderate techniques including ABG, intubation, and IV cannulation.
- Performed wound dressing, stitching, and nasogastric tube insertion procedures.
- Completed CPR and ECG interpretations to assess patient conditions.
Internal Medicine Resident Doctor
El-Alamein Central Hospital
Matrouh
10.2016 - 08.2017
- Conducted follow-up assessments for chronic diseases, including diabetes and hypertension.
- Managed emergency calls, differentiating between urgent and non-urgent cases.
- Facilitated referrals for patients requiring specialised care.
- Provided on-call support across various departments to ensure continuity of care.
Chest Medicine Resident
Ministry of Health, Egypt
Alexandria
05.2016 - 10.2016
- Collected samples from 30 patients using flexible bronchoscopy.
- Managed A&E operations, ensuring adherence to treatment plans for in-patients.
- Coordinated discharge processes for patients, streamlining transitions.
General Practitioner
Ministry of Health, Preventive Sector
06.2015 - 05.2016
- Managed chronic patients with diabetes, hypertension, and ischaemic heart disease.
- Conducted weekly health education sessions to increase awareness of endemic diseases.
- Promoted infection control measures and child and maternal care practices.
- Advocated for importance of vaccination programmes among community members.
House Officer
Alexandria Main University Hospitals
Alexandria
03.2014 - 03.2015
- Completed rotations in Internal Medicine, Paediatrics, Emergency Medicine, Chest Medicine, Neurology, Gynaecology, Plastic Surgery, and Anaesthesia.
- Assisted in various surgical procedures including appendectomy and craniotomy.
- Acquired skills in advanced techniques such as CVC placement and intubation.
Education
B.SC degree Of Medicine and Surgery - Medicine and surgery
Alexandria University
EgyptDiploma in pharmaceutical medicine - Pharmaceutical Medicine
Faculty of Pharmaceutical Medicine
United KingdomSkills
Clinical Trials Management I Research Ethics I MHRA Regulations I Protocol Review I Investigator Brochure Review I Consent Form Review I Study Manual Review I Physical Examination I Lab Work Review I ECG Review I Cardiac Safety Trials I DDI Trials I Data Analysis I Dose Escalation I Adverse Event Management I Clinical Evaluation I Case Report Form Review I Study Reporting I Clinical Research I Patient Safety I Study Protocol Compliance I Risk Assessment I Medical Documentation I Patient Interaction I Team Collaboration I Trial Oversight I Evidence Analysis I Team Leadership I Decision Making I Effective Communication I Time Management I People Management I Risk Management I Pharmacovigilance I REC Submissions I Regulatory Submissions I Study Report Review I Safety Meetings I Early Phase Trials I First in Human Trials I In-Depth knowledge of GCP
Websites, Portfolios and Profiles
https://www.linkedin.com/in/nadine-abdullah-3689b8
Timeline
Principal Investigator
Celerion GB ltd
05.2021 - 11.2025
Clinical Research Physician
Medinova Warwickshire Quality Research Site
10.2019 - 05.2021
Medical Practitioner
Dr. Aly M. ABDELKARIM Urology Clinic
02.2019 - 10.2019
House Officer
Maldives Ministry of Health
09.2017 - 09.2018
Internal Medicine Resident Doctor
El-Alamein Central Hospital
10.2016 - 08.2017
Chest Medicine Resident
Ministry of Health, Egypt
05.2016 - 10.2016
General Practitioner
Ministry of Health, Preventive Sector
06.2015 - 05.2016
House Officer
Alexandria Main University Hospitals
03.2014 - 03.2015
B.SC degree Of Medicine and Surgery - Medicine and surgery
Alexandria University
Diploma in pharmaceutical medicine - Pharmaceutical Medicine
Faculty of Pharmaceutical Medicine