Schineez Fernandes
Glasgow
Summary
Detail-oriented researcher in cancer research and precision oncology, skilled in biotechnology, molecular biology, and immunology. Experienced in designing and executing laboratory experiments, including CRISPR-Cas9 gene editing and advanced analytical techniques. Demonstrates strong critical thinking and data interpretation capabilities, ensuring accuracy and scientific integrity in collaborative environments.
Overview
3
3
years of professional experience
Work History
Research Intern – Cancer Biology & Functional Genomics
CRUK Beatson Institute
Glasgow
06.2025 - 08.2025
- Designed and executed CRISPR-Cas9 gene knockout experiments targeting candidate genes (PRTN3 and CD34).
- Generated stable knockout populations using ER-HOXB8 immortalised murine bone marrow progenitor cells.
- Executed lentiviral transduction with puromycin selection to enrich edited cell populations for downstream applications.
- Quantified gene expression changes using quantitative PCR (qPCR).
- Investigated mechanisms of monocyte-mediated chemoresistance in biliary tract cancers.
- Conducted cell viability and proliferation assays using staining techniques and high-content imaging (Opera Phoenix Plus).
- Evaluated the drug sensitivity of cancer cell lines under selective pressure conditions.
- Applied flow cytometry and magnetic cell sorting techniques for cell population analysis and enrichment.
- Diagnosed experimental limitations and collaborated on troubleshooting to enhance assay consistency.
- Developed reproducible workflows for gene editing and functional validation, ensuring reliable experimental outcomes.
- Conducted research at Wolfson Wohl Cancer Research Centre in Glasgow
Front Desk & Bar Team Member
Shiso Bar & Restaurant
Glasgow
02.2025 - 03.2025
- Provided exceptional customer service to enhance guest experiences in fast-paced environment.
- Adapted to high-pressure situations while effectively collaborating with team members to maintain service quality.
- Trained and guided new staff to ensure seamless integration into team operations.
Quality Control & Quality Assurance Intern
Goa Dairy
Goa
05.2023 - 06.2023
- Conducted microbiological and chemical analyses on dairy products to ensure compliance with quality standards.
- Assisted in the implementation of quality assurance protocols aligned with food safety regulations.
- Performed pH testing and microbial enumeration to assess product safety and quality.
- Evaluated hygiene standards to identify and mitigate potential contamination risks.
Laboratory Intern (Clinical Diagnostics)
Atul Path Lab
Goa
07.2022
- Performed specimen collection, processing, and analysis to support accurate test results.
- Maintained strict adherence to quality control and regulatory protocols to ensure compliance and reliability.
- Assisted in routine clinical diagnostic testing and streamlined laboratory workflows.
- Operated laboratory equipment ensuring calibration and maintenance.
- Communicated effectively with healthcare staff regarding test procedures and results.
Education
MSc - Cancer Research and Precision Oncology
University of Glasgow
Glasgow, UK01-2025
BSc - Biotechnology (Honours)
Parvatibai Chowgule College of Arts & Science
Goa, India01-2024
Skills
- PCR
- QPCR
- Gel Electrophoresis
- Western Blotting
- Northern Blotting
- Southern Blotting
- Gene editing
- Mutagenesis
- Lentiviral Transduction
- Gene transfer
- Mammalian Cell Culture
- Cell Line Development
- Pathogen Identification
- Flow Cytometry
- Cell sorting
- Magnetic Cell Sorting
- Immunohistochemistry
- ELISA
- Fluorescence imaging
- Confocal Microscopy
- Light Microscopy
- Viability assays
- Proliferation assays
- Spectrophotometric Assays
- Bioinformatics
- Data analysis
- Data Interpretation
- Experimental Design
- Troubleshooting
- Analytical Method Development
- Protein Analysis
- Microbiological Techniques
- Chromatography Techniques
- Quality assurance
- Scientific Reporting
- Scientific reporting
- Teamwork
- Adaptability
- Time Management
- Multitasking
- Leadership
- Presentation
- Multitasking
Languages
English
Hindi
Konkani
Custom Section
- Co-President, Biochrome Club, Organised workshops, academic discussions, and networking events.
- Organiser, Synapse Conference (2023 & 2024), Managed event logistics and coordinated scientific programming., Participated in workshops on advanced molecular biology techniques.
Research
Research Intern – Cancer Biology & Functional Genomics, CRUK Beatson Institute / Wolfson Wohl Cancer Research Centre, Glasgow, 2025-06-01, 2025-08-01, Investigated mechanisms of monocyte-mediated chemoresistance in biliary tract cancers., Designed and executed CRISPR-Cas9 gene knockout experiments targeting candidate genes (PRTN3 and CD34)., Generated stable knockout populations using ER-HOXB8 immortalised murine bone marrow progenitor cells., Performed lentiviral transduction followed by antibiotic (puromycin) selection to enrich edited cell populations., Quantified gene expression changes using quantitative PCR (qPCR)., Conducted cell viability and proliferation assays using staining techniques and high-content imaging (Opera Phoenix Plus)., Evaluated the drug sensitivity of cancer cell lines under selective pressure conditions., Applied flow cytometry and magnetic cell sorting techniques for cell population analysis and enrichment., Identified experimental limitations and contributed to troubleshooting assay inconsistencies., Established reproducible workflows for gene editing and functional validation studies.
Additional information
Strong interest in oncology research, immunotherapy, and translational medicine., Experienced in working in both academic and industry laboratory settings., Willing to relocate and open to research, clinical, or industry-based roles.
Projects
- Monocyte-Mediated Chemoresistance in Biliary Tract Cancer (Master’s Project), Investigated the role of immune cell gene expression in chemotherapy resistance. Developed CRISPR-based gene knockout models for functional validation. Analysed gene expression and cellular response under drug selection conditions.
- Assessment of Phytoremediation Potential of Salvinia molesta, Evaluated the capacity of aquatic ferns to remove environmental pollutants. Conducted experimental studies on pollutant uptake and environmental impact.
Timeline
Research Intern – Cancer Biology & Functional Genomics
CRUK Beatson Institute
06.2025 - 08.2025
Front Desk & Bar Team Member
Shiso Bar & Restaurant
02.2025 - 03.2025
Quality Control & Quality Assurance Intern
Goa Dairy
05.2023 - 06.2023
Laboratory Intern (Clinical Diagnostics)
Atul Path Lab
07.2022
MSc - Cancer Research and Precision Oncology
University of Glasgow
BSc - Biotechnology (Honours)
Parvatibai Chowgule College of Arts & Science