Megha Bhandari

I have developed my knowledge and experience in Medicine working as a doctor over the past four years to build a strong clinical foundation for my future career and am looking forward to stepping up to work as a medical registrar over the next year. At the same time, I have been struck by the impact of the application of big data analysis to medical data. I find the point where Medicine, Mathematics and Computer science interact incredibly fascinating, and this is where I would like to place myself in the future.

1. Project Title: ITU Covid CXR (March - May 2021)

My role: I created a Machine learning image classifier of CXRs of Covid Patients to differentiate between patients that did v did not respond to steroids, ongoing analysis and write up with ITU team

2. Project Title: Acute Variceal bleeding :5 year analysis (Jan – March 2021)

My role: Statistical analysis, writing of abstract, poster presentation at National Meeting BASL 2021

3. Project Title: EUS Guided Drainage of Pancreatic Fluid Collections (Jan – March 2021)

My role: Statistical analysis, contribution to writing of abstract, oral presentation at National Meeting BSG 2021

4. Project Title: Colonoscopy Withdrawal Time (Jan – March 2021)

My role: Statistical analysis, writing of abstract, presentation of poster at International conference ESGE March2021

5. Project Title: Management of large and complex colonic polyps (Jan-March 2018)

My role: Literature review, presenting data in tabular form, contribution to writing of manuscript

6. Project Title: Inflammatory Bowel Disease: Multicentre Study (August – October 2019)

My role: Collating data from multiple centres, literature review, statistical analysis, contribution to writing of manuscript

○ Data mining skills using OMIM databases

○ Proficient in using Ensemble genome browser

○ Using MolBrowser (interactive molecular graphics software) to visualize and manipulate the three dimensional structures of biomolecules

○ PCR primer designing

2.  Wet Lab Skills:

o Project Design – designed my own experiment to de

o termine an unknown toxin and its site of action in the respiratory chain

o Developing and standardising assays

o ELISA

o SDS PAGE

o Gel Filtration column chromatography

o Restriction mapping

Bradford Assay

2. Silence of the LAMS: Reducing Risk in EUS Guided Drainage of Pancreatic Fluid Collections – oral presentation at National Meeting BSG 2021 GUT (Megha Bhandari, Puneet Chhabra, Matthew Stammers, Nadeem Tehami, Ben Maher)

3. Acute Variceal bleeding in a large teaching hospital: a 5 year analysis – poster presentation at National Meeting BASL 2021 (Anju Phoolchund, Megha Bhandari, Luigi Medri, Srishti Sarkar, Chanice Bloomfield, Phillip Oppong, Imdadur Rahman, Phillip Boger, Praful Patel)

4. Machine Learning Pandemic Risk Stratification Prediction (Megha Bhandari, Matthew Stammers) – Poster presentation at the National RSM Gut Club March 2022

5. Predictive analysis: determinants of AKI in patients undergoing cardiothoracic surgery (Megha Bhandari, Jason Ali) – Poster presentation at the National Society of Cardiothoracic Surgeons 2024

1. Current East of England Deanery representative for Education and Quality Improvement

2. Current Anatomy Demonstrator University of Cambridge

3. Current Clinical supervisor for 4th year medical students University of Cambridge

4. Current Physiology supervisor for 1styear medical students University of Cambridge

5. I am a co-founder of the organisation MedHelp, which was set up to provide teaching and support to medical and biomedical students when lectures were mostly online during the pandemic. I designed and organized a teaching programme and recruited volunteer junior doctors and other medical students to deliver teaching sessions to students at medical schools across the UK over a period of 6 months. I have evidence of formal feedback from these sessions.

6. I was a teacher for BiteMedicine National Study Group Programme. In this role I helped design materials and delivered hourly teaching sessions to students at medical schools from around the United Kingdom and beyond over a period of three months. I have evidence of formal feedback from these sessions.

7. Tomorrow’s Teachers Course and Integrated Foundation of Medical Education diploma

1. ScRNA Immunomodulation in Cardiovascular disease (Dr Tian Zhao, University of Cambridge)

2. Diagnostic yield of endoscopic ultrasound-guided liver biopsy in comparison to percutaneous liver biopsy: a meta-analysis of randomized controlled trials and trial sequential analysis (Dr Facciorusso, Ospedali Riuniti di Foggia)

3. Systematic Review and Meta-analysis of cardiac risk associated with antiepileptic medication (Dr Sia, National University of Singapore)

6. Ongoing Genomics project involving manual curation of Monogenic variants involved in IBD (Professor Ennis, Central and South Genomic Medicine Service Alliance)

7. Pathway Analysis to identify IBD responders to biologic treatments (Dr Subramanian, Department of Gastroenterology, Addenbrookes)

8. HackMed Sheffield      Hackathon Finalist - created a website that connected hospitals to the      best repurposed oxygen supplier and generated the optimal route to deliver      this oxygen. This was to help with the real world problem of the covid      crisis and lack of medical oxygen in India at the time. https://devpost.com/software/mediconnect?ref_content=my-projects-tab&ref_feature=my_projects

Professor Rebecca Fitzgerald

OBE, MACantab, MD, FMedSci, EMBO

Early Cancer Institute

University of Cambridge

rcf29@cam.ac.uk

(Academic reference, previous Director of Studies)

Dr Steven Wallis FRCP

Consultant Physician DME

Divisional Director, Division C

Addenbrookes Hospital

Cambridge

stephenwallis@nhs.net

(Professional reference, Current Clinical Supervisor)