Meetakshi Gupta
Abingdon,UK
Summary
A highly skilled professional with expertise in gynaecological and breast cancers. Specialises in systemic treatments, immunotherapy, IMRT, Volumetric Modulated Radiotherapy. Demonstrates proficiency in advanced techniques such as Deep Inspiratory Breath Hold and 4DCT. Possesses thorough training and special interest in interstitial and intrauterine brachytherapy, including MR guided brachytherapy. Experienced in conducting animal experiments and basic research procedures like ELISA, RT-PCR, and immunofluorescence analysis at Princess Margaret Cancer Centre. Committed to advancing cancer treatment through innovative research and clinical excellence.
Overview
15
15
years of professional experience
2021
2021
years of post-secondary education
Work history
Consultant Clinical Oncologist
Oxford University Hospitals NHS Foundation Trust
Oxford, Oxfordshire
12.2024 - Current
- I treat gynaecological and breast cancers. I provide new patient consultations as well as follow ups.
- I provide radiotherapy, chemotherapy, targeted therapy and immunotherapy treatments.
- I specialise in brachytherapy treatments for gynaecological cancers.
- I am part of the MDTs and provide recommendation as well as discuss my patients in weekly meetings.
- I also run satellite clinic at Stoke Mandeville hospital fortnightly.
- I cover inpatients and on-calls.
- I recently participated in updating the gynaecological protocols and changing fundamental component of brachytherapy treatments.
- I am part of ongoing clinical trials and actively recruit patients to these.
- I am looking at opening more clinical trials at the centre.
- I manage Medical students' placements in Oncology
Consultant Clinical Oncology, Gynae-Oncology and breast
Barking Havering and Redbridge University Hospitals NHS Trust
Romford
11.2023 - 11.2024
- I was the only Clinical Oncologist treating Gynaecological malignancies at Queen's hospital. I re-established the gynae radiotherapy service after a gap of 2 years. I was responsible for radiotherapy and systemic treatments of gynae-oncology patients.
- I was part of the consultant on-call rota and registrar teaching rota.
- I worked with the team at Barts and present cases in the regional MDT (north-east London Alliance) and perform brachytherapy procedures as Honorary Consultant Clinical Oncology (St Bartholomew Hospital).
- I worked on a project looking at the potential of daily online adaptive planning for gynae malignancies on ETHOS.
- I wrote new patient information leaflets for patients receiving external beam radiotherapy and/or brachytherapy. I also developed new information leaflets on constipation, menopause and lymphedema management.
- I wrote CT simulation protocol and online matching protocols for gynae patients and currently working on the clinical protocols.
- I was also 1 of 3 breast oncologists and do radiotherapy and systemic treatments.
- Full-time 10 PA
Locum Consultant Clinical Oncology, Gynae-Oncology
Guy’s and St Thomas NHS FT
London
07.2022 - 11.2023
- I worked as one of 4 Clinical Oncology Consultants treating Gynaecological cancers.
- I had independent follow up, new patient and on-treat clinics.
- I was responsible for radiotherapy and systemic therapy treatments of gynaecological malignancies and case presentation in multidisciplinary meeting.
- I performed brachytherapy insertions and planning- intrauterine, interstitial, vaginal for gynaecological cancers.
- I was part of on-call consultant rota- 1 in 25 and Consultant of the week duties- responsible for all oncology inpatients and inpatient radiotherapy referrals including MSCC.
- I worked on a quality improvement project to reduce the nodal PTV margins from 7 to 5mm for Gynae- oncology patients and was part of the team establishing Plan of the day treatment for cervical cancer patients being treated with definitive radiotherapy.
- I was the only Oncologist treating thyroid malignancies between Feb 2023- May 2023. This included adjuvant and palliative radiotherapy and all systemic treatments- TKI, IO and chemotherapy.
- Part-time 8 PA
Clinical Research Fellow
University College London Hospitals NHS FT
London
07.2021 - 07.2022
- I had 50% clinical and 50% research duties. I was responsible for clinical duties in Neuro-oncology including radiotherapy and chemotherapy treatments and follow up clinics.
- I was on the oncology registrar inpatient and on-call rota which comprised management of both Clinical and Medical Oncology inpatients (oncology and medical emergencies, delivery of inpatient chemotherapy, managing A&E referrals, externals referrals and transfers, elective admissions for nephrostomy insertion, unsealed source radiotherapy, etc)
- Research: I worked on several projects as part of my clinical research and presented the results in conferences
- ‘Evaluation of late perfusion changes in cortical blood flow >1 year after radiation for glioma using arterial spin labelling MRI’- poster discussion in ESTRO 2022.
- ‘Development of prospective trial for mid-treatment biological image guided adaptive radiotherapy (BIGART) for glioblastoma’- poster discussion in ESTRO 2022.
- ‘Palliative carboplatin chemotherapy in previously treated high-grade glioma: real-world efficacy and safety’- poster presentation BNOS 2022.
- I was also responsible for organizing and facilitating academic sessions for the specialty registrars in oncology from Sept 2021 to March 2022.
- Full time, 40 hours/week
- Supervisor: Michael Kosmin
Research Assistant
Department of Paediatric Oncology, Sir Gangaram Hospital
New Delhi
01.2021 - 06.2021
- I was responsible for clinical activities in paediatric oncology clinic.
- Responsible for research activities ongoing in the department- consenting patients, log keeping, review of literature.
- Full time, 40 hours/week
- Supervisor: Anupam Sachdeva
Clinical Research Fellow
Princess Margaret Cancer Centre
Toronto
07.2018 - 07.2020
- This was 80% research and 20% clinical fellowship.
- I was responsible for Gynae-oncology clinics including new patients, on-treatment reviews and follow ups.
- Also included management of inpatients (acute illnesses, medical emergencies and radiation toxicity), case presentation in multidisciplinary meeting, radiotherapy prescription, contouring and planning and online imaging review.
- I was on the on-call rota (attending to medical code, responding to out-of-hours patient calls and outside referrals)
- I was involved in MR guided brachytherapy (intracavitary, interstitial and vaginal vault) which also included the EBRACE II patients.
- Research: I was heavily involved in preclinical research including animal experiments and basic research (Lab-Dr. Michael Milosevic and Dr. Richard Hill). My main project was ‘Radiation-Induced Upregulation of CXCL12/CXCR4 Signaling In Cancer -Understanding The Mechanism To Guide Biomarker Development’.
- I received 3 awards including 2 grants for my work.
- I attended multiple courses at the University of Toronto including Clinical and Experimental Radiobiology, Immunotherapy, Clinical Investigator Program, Seminars in Translational Research.
- Full time, 40 hours/week
- Supervisor: Michael Milosevic
Senior resident
Tata Memorial Centre
Mumbai
09.2016 - 06.2018
- It was a training post, which included full time clinics (8 per week), including out-patient and in-patient departments, radiotherapy contouring, planning, imaging review and on-treatment review and systemic therapy.
- Management of acute emergencies and other medical issues, brachytherapy rotation including gynaecological, breast, head neck and sarcoma cases with CT and MR based planning, chemotherapy prescription, academic presentations, and research publications.
- I was also responsible for junior teaching and mentorship. Journal club presentations, rota co-ordination for residents.
- Brachytherapy rotation including gynaecological, breast, head neck and sarcoma cases with CT and MR based planning.
- Academic presentations, and research publications.
- I completed my MD dissertation on: ‘Clinical utility of baseline 18F-flouro-deoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) in the diagnosis and staging of primary central nervous system lymphoma (PCNSL): results from a prospective study’.
- I presented my work in ASTRO 2017 and have 2 publications from this work.
- I developed 2 prospective trials at “International Collaboration for Research methods Development in Oncology (CReDO) workshop” one of which is still ongoing- NCT03007110.
- I was a part of multiple audit projects including development of SOP for management of oncological emergencies and radiotherapy planning pathway.
- Full time
- Supervisor: Dr. Sarbani Ghosh Laskar
Post graduate resident
Tata Memorial Centre
Mumbai
07.2013 - 08.2016
- It was a junior training post which included full time clinics (8 per week), including out-patient and in-patient departments, radiotherapy contouring, planning, imaging review and on-treatment review and systemic therapy.
- Management of acute emergencies and other medical issues.
- Full time
- Supervisor: Dr. Tejpal Gupta
House job
Sir Ganga Ram Hospital
New Delhi
02.2011 - 02.2012
- Medical internship as part of MBBS curriculum
- Full time, 40 hours/week
- Supervisor: Anupam Sachdeva
Education
Fellowship of the Royal College of Radiologists -
Royal College of Radiologists
Doctor of Medicine - Radiotherapy
Tata Memorial Centre
Bachelor of Medicine and Surgery - undefined
Bharati Vidyapeeth Deemed University
Skills
- I have expertise in Stereotactic Radiosurgery, Stereotactic Ablative Radiotherapy, Volumetric Modulated Radiotherapy, Deep Inspiratory Breath Hold, 4DCT
- I have thorough training in interstitial and intrauterine brachytherapy and MR guided brachytherapy
- I trained in animal experiments and basic research procedures like ELISA, RT-PCR, immunofluorescence analysis at Princess Margaret Cancer Centre
Affiliations
- Reading, writing, dancing
Awards
2020 Chair's Award for Academic Excellence in Research, University of Toronto, Department of Radiation Oncology, 2020, 2020 Hold'em for Life Clinician Scientist award, University of Toronto, 2020, 2019 Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21) scholarship, University of Toronto, 2019., 2019 Best group presentation at STARS21 program- AI in Healthcare (PRO)., 2016 21st Indian College of Radiation Oncologists course quiz and travel scholarship for AROICON 2016.
Publications
- 2025 Sarbani Ghosh Laskar, Shwetabh Sinha, Meenakshi Jeeva, Meetakshi Gupta et al. Prophylactic Versus Reactive (PvR) Feeding in Patients Undergoing (Chemo)radiation in Head and Neck Cancers: Results of a Phase III Randomized Controlled Trial; Head and Neck https://doi.org/10.1002/hed.28244
- 2023 Sarbani Ghosh Laskar, Shwetabh Sinha, Meetakshi Gupta et al. Prophylactic versus reactive feeding approach in patients undergoing adjuvant radiation therapy for oral cavity squamous cell carcinoma: A propensity score matched-pair analysis; Head and Neck 2023; https://doi.org/10.1002/hed.27336
- 2022 Jordan Colman, Laura Mancini, Spyros Manolopoulos, Meetakshi Gupta et al; Is Diffusion Tensor Imaging-Guided Radiotherapy the New State-of-the-Art? A Review of the Current Literature and Technical Insights; January 2022 Applied Sciences 12(2):816 DOI:10.3390/app12020816
- 2022 Alice Maguire, Emeka Obasi, Julia Markus, Meetakshi Gupta et al; Early Post-treatment Pseudo-continuous Arterial Spin Labelling Stratifies 12 Month Survival in Gliomas; October 2022Neuro-Oncology 24(Supplement_4):iv8-iv8 DOI:10.1093/neuonc/noac200.036
- 2022 Tejpal Gupta, Prashant Nayak, Yamini Baviskar, Meetakshi Gupta et al. Systemic inflammatory biomarkers in primary central nervous system lymphoma versus high-grade glioma: exploratory, comparative and correlative analysis; CNS Oncology 2022; https://doi.org/10.2217/cns-2022-0004
- 2020 M Gupta et al. Single-lung stereotactic body radiotherapy: A case report and discussion of therapeutic challenges; Lung India doi: 10.4103/lungindia.lungindia_281_19
- 2020 Jai Prakash Agarwal, Avinash Pilar, Naveen Mummudi, Meetakshi Gupta et al. Stereotactic body radiation therapy for medically inoperable early-stage lung cancer: Tata Memorial Hospital perspective and practice recommendations; Indian Journal of Cancer DOI: 10.4103/ijc.IJC_216_18
- 2019 Gupta M, Gupta T, et al. Utility of flouro-deoxy-glucose positron emission tomography/computed tomography in the diagnostic and staging evaluation of patients with primary CNS lymphoma. CNS Oncol 2019, doi: 10.2217/cns-2019-0016.
- 2019 Meetakshi Gupta, Supriya Chopra, et al. Early toxicity and Treatment Outcomes of Extended Field-Intensity Modulated Radiotherapy (EFIMRT) for Cervical Cancer Patients with Para-Aortic Nodal Metastasis. Ecancermedicalscience 2019. doi: 10.3332/ecancer.2019.957.
- 2019 Gupta T, Gupta M, et al. Diagnostic Performance of Baseline 18F-Fluoro-DeoxyGlucose Positron Emission Tomography/Computed Tomography in Patients with Clinico-Radiological Suspicion of Primary Central Nervous System Lymphoma. Annals of Hematology & Oncology, 2019, DOI:10.26420/annhematoloncol.2019.1228.
- 2018 V. Murthy, M. Gupta, et al Early Results of Extreme Hypofractionation Using Stereotactic Body Radiation Therapy for High-risk, Very High-risk and Node-positive Prostate Cancer. Clinical Oncology, 2018, https://doi.org/10.1016/j.clon.2018.03.004.
- 2018 Gupta M, Gamre P,et al. Effect of Imaging Frequency on PTV Margins and Geographical Miss during Image-Guided Radiotherapy for Prostate Cancer. Pract Radiat Oncol 2018, http://dx.doi.org/10.1016/j.prro.2017.09.010
- 2018 Chopra Supriya, Gupta Meetakshi, et al Locally advanced cervical cancer: A study of 5-year outcomes. Indian Journal of Cancer 2018, http://dx.doi.org/10.4103/ijc.IJC_428_17
- 2017 Pilar A, Gupta M, Laskar SG, Laskar S. Intraoperative Radiotherapy: Review of Techniques and Results. Ecancermedicalscience 2017, https://doi.org/10.3332/ecancer.2017.751.
- 2022 Poster discussion ESTRO 2022 “Evaluation of late perfusion changes in cortical blood flow >1 year after radiation for glioma using arterial spin labelling MRI”
- 2022 Poster discussion ESTRO 2022
- ‘Development of prospective trial for mid-treatment biological image guided adaptive radiotherapy (BIGART) for glioblastoma’
- 2019 Poster presentation and pitch: Radiation-Induced, Hypoxia-Dependent Upregulation Of CXCL12/CXCR4 Signalling In Cervical Cancer at the annual UTDRO Research Day
- 2017 Oral presentation: Single Lung Stereotactic Body Radiotherapy (SLABR) at the Indian Cancer Congress, Bangalore, 2017.
- 2017 Invited talk: ‘Adaptive Image-Guided Radiotherapy for prostate cancer’ at XVth TMH Annual Radiotherapy Practicum on “Adaptive Radiotherapy in Practice”, 2017
- 2017 Oral presentation: ‘Clinical Utility of Baseline 18-F FDG-PET/CT in Prognostication of Patients with Primary Central Nervous System Lymphoma (PCNSL)’ at the 59th annual ASTRO conference (San Diego, September 2017).
- 2017 Doctoral debate presentation: Against the motion on ‘There is role of ITV-to-PTV margins in the era of IGRT’ in the regional chapter of Association of Radiation Oncologists of India (AROI) 2017 conference which featured as the high point of the meet in the annual AROI newsletter.
- 2015 Poster presentation: Early results of MD dissertation ‘Clinical Utility of F-18 FDG-PET/CT in Primary Central nervous System Lymphoma’ at Indian Cooperative Oncology Network conference 2015.
- 2015 Poster presentation: in Best Paper category on ‘Comparison of Volumetric Modulated Arc Therapy (RapidArc) And Sliding Window IMRT for Early Oropharyngeal Cancers: A Treatment Planning Study’ in annual AROI-CON 2015.
Training
- 2019-2020 The Strategic Training in Transdisciplinary Radiation Science (STARS21) program, Department of Radiation Oncology, University of Toronto, November 2019- May 2020.
- 2020 Clinical and Experimental Radiobiology course, University of Toronto, May 2020.
- 2020 Immunotherapy course, Department of Medical Biophysics, University of Toronto, January-April 2020.
- 2020 Seminars in Translational Research, Institute of Medical Science, University of Toronto, September– December 2020.
- 2019 Clinical Investigator Program, CorEd, Online module 2019.
- 2019 Proton Therapy Co-Operative Group annual meeting at Manchester. Educational and Scientific sessions. June 10th -15th, 2019.
- 2018 A Vision for Proton Therapy in Ontario organized by the University of Toronto. 2018.
- 2018 The Expanding use of SBRT in Radiation Therapy. A two-day workshop organized by University of Toronto, Department of Radiation Oncology, 2018.
- 2018 Terry Fox Research Institute's, Ontario Node Research Symposium, December 2018.
- 2017 Participated in “International Collaboration for Research methods Development in Oncology (CReDO) workshop” held in collaboration of King’s College London, Medical Research Council Clinical Trials Unit (MRC-CTU) University College London, Australia and Asia-Pacific Clinical Oncology Research and Development (ACORD) group and Tata Memorial centre Mumbai in March 2017.
Registrations and Memberships
- 2023: Certificate of Eligibility for Specialist Registration in Clinical Oncology
- 2021: General Medical Council (Registration No- 7869686)
- 2013: Medical Council of India
- 2021: Member of the Royal College of Radiologists
- 2021: Member of European Society Radiation Oncology
- 2017: Member of American Society for Radiation Oncology
- 2017: Member of American Society Clinical Oncology
- 2013: Member of Association of Radiation Oncologists of India
Research Experience
- 2022-23 MRI guided adaptive brachytherapy in locally advanced cervical cancer: 10-year efficacy and toxicity outcomes
- 2021-22 Evaluation of late perfusion changes in cortical blood flow >1 year after radiation for glioma using arterial spin labelling MRI- a retrospective analysis of ASL imaging to look at late effects of RT on normal brain
- 2021-22 Development of prospective trial for mid-treatment biological image guided adaptive radiotherapy (BIGART) for glioblastoma-prospective single arm clinical trial. I screened and accrued patients on the trial, helped develop biological target volume for adaptive radiotherapy and contributed to a review article.
- 2022 Palliative carboplatin chemotherapy in previously treated high-grade glioma: real-world efficacy and safety- retrospective analysis
- 2018-2020 Targeting radiation-induced CXCL12/CXCR4 signalling and immune microenvironment to improve radio-curability of human cancers- pre-clinical research involving orthotopic xenografts and wet lab experiments.
Management experience
- Medical student placement- oncology co-ordinator at OUH
- Clinical supervisor: Clinical supervisor for SHO and overseas students
- Teaching co-ordination ay UCLH Sept 2021-March 2022: I maintained the rota, contacted consultants for arranging academic sessions, co-ordinated pharma rep sessions. I also maintained attendance log and recorded the sessions for registrars who were unable to attend.
Timeline
Consultant Clinical Oncologist
Oxford University Hospitals NHS Foundation Trust
12.2024 - Current
Consultant Clinical Oncology, Gynae-Oncology and breast
Barking Havering and Redbridge University Hospitals NHS Trust
11.2023 - 11.2024
Locum Consultant Clinical Oncology, Gynae-Oncology
Guy’s and St Thomas NHS FT
07.2022 - 11.2023
Clinical Research Fellow
University College London Hospitals NHS FT
07.2021 - 07.2022
Research Assistant
Department of Paediatric Oncology, Sir Gangaram Hospital
01.2021 - 06.2021
Clinical Research Fellow
Princess Margaret Cancer Centre
07.2018 - 07.2020
Senior resident
Tata Memorial Centre
09.2016 - 06.2018
Post graduate resident
Tata Memorial Centre
07.2013 - 08.2016
House job
Sir Ganga Ram Hospital
02.2011 - 02.2012
Doctor of Medicine - Radiotherapy
Tata Memorial Centre
Bachelor of Medicine and Surgery - undefined
Bharati Vidyapeeth Deemed University
Fellowship of the Royal College of Radiologists -
Royal College of Radiologists
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