Matthew Nesbitt
Nelson,Caerphilly County Borough
Summary
Medicinal chemistry graduate with distinction-level research experience in drug design and optimisation, with targeted training in nucleic acids, bioconjugation, and chemical biology. Experienced in synthesising and characterising novel therapeutic candidates and applying data-driven approaches to guide experimental design. Motivated to apply chemical expertise to the development of next-generation therapeutics at the chemistry-biology interface.
Overview
6
6
years of professional experience
Work history
Bartender
Depot
2024.08 - 2026.05
- Operate in high-pressure, fast-paced environments requiring efficiency and accuracy
- Manage customer interactions and resolve conflicts, strengthening communication and stakeholder handling skills
- Maintain organisation of stock and service flow, ensuring smooth operational delivery whilst supervising colleagues
Store Assistant
Toolstation
2021.07 - 2021.08
- Worked in time critical environments requiring precision and efficiency
- Maintained accuracy in order fulfilment, contributing to customer satisfaction
- Adapted to multiple roles under pressure, supporting overall team performance
Biology & Chemistry Tutor
Educalis
2020.09 - 2021.03
- Delivered tailored lesson plans, simplifying complex concepts for students
- Strengthened communication skills by adapting explanations to different learning styles
- Collaborated with peers to improve teaching strategies through structured feedback
Education
MSc - Medicinal Chemistry
Cardiff University
BSc - Chemistry
Cardiff University
Skills
Laboratory Skills
- Organic synthesis and compound characterisation
- Analytical techniques (NMR, LC-MS, Prep TLC, IR)
Research & Analytical Skills
- Experimental design and optimisation
- Experimental analysis (Mestrenova, TopSpin)
- Communicating to senior peers via presentations
Computational/Data Skills
- SQL (data query, joins, filtering)
- Tableau (data visualisation)
Research Experience
MSc Research Project - Design of ProTide Based Therapeutics for Cystinosis (Distinction)
Cardiff University
- Designed and synthesised two novel ProTide-based drug candidates targeting cysteine accumulation
- Applied structure-activity relationships (SAR) to iteratively optimise molecular design
- Performed compound characterisation using NMR and LC-MS
- Integrated physicochemical and biological considerations to improve stability and translational potential
- Analysed complex experimental datasets to guide design decisions and reduce iterative insufficiencies
- Collaborated within a research environment to align experimental outcomes and project objectives
www.linkedin.com/in/matthew-nesbitt-6320242b6
References
Available on request
Languages
English
Fluent
Timeline
Bartender
Depot
2024.08 - 2026.05
Store Assistant
Toolstation
2021.07 - 2021.08
Biology & Chemistry Tutor
Educalis
2020.09 - 2021.03
MSc - Medicinal Chemistry
Cardiff University
BSc - Chemistry
Cardiff University