Summary
Overview
Work history
Education
Skills
REFERENCES
AWARDS AND SCHOLARSHIPS
PEER-REVIEWED PUBLICATIONS
LEADERSHIP AND MENTORING
TEACHING EXPERIENCE
SERVICE TO PROFESSION – REVIEWER FOR JOURNAL
OUTREACH AND OTHER ACTIVITIES
Timeline
Generic

Kawarpal Singh

Cambridge

Summary

NMR Spectroscopist with 10 years of experience in small molecule solution state, specializing in one-and two-dimensional NMR for reaction monitoring and structure elucidation. Developed advanced multiple-quantum Ultrafast 2D NMR techniques at high-field, optimizing performance of Bruker and Magritek instruments. Delivered user training and implemented innovative solutions for small molecule analysis for process control at low-field using chemometrics and data analytical tools.

Overview

16
16
years of professional experience
10
10
years of post-secondary education

Work history

Marie Sklodowska-Curie Actions – Postdoctoral Fellow (MSCA-PF)

University of Cambridge
Cambridge
2025.01 - Current
  • Conducted research under supervision of Prof. Dame Clare P. Grey, FRS, focusing on multidimensional NMR techniques.
  • Developed innovative in-situ NMR methods for analysing phenazine-based redox flow batteries.
  • Executed experimental protocols to enhance understanding of redox behaviour in batteries using ex-situ NMR.

Postdoctoral Research Associate with Shell, Amsterdam

University of Cambridge
Cambridge
2023.02 - 2025.12
  • Conducted research on redox-flow batteries, emphasising reaction chemistry using NMR, MRI, and DNP methods.
  • Mentored graduate students in solution-state NMR and MRI techniques to facilitate knowledge transfer.

Postdoctoral fellow

Radboud University
Nijmegen
2022.04 - 2023.01
  • Developed high-throughput drug screening methodologies using NMR, DNP, and MRI techniques.
  • Implemented hyperpolarized rapid-melt and freeze DNP methodologies for drug discovery applications.
  • Conducted T1 and T2 weighted experiments with 1D spectroscopic imaging for mixture analysis.
  • Leveraged localized magnetic resonance imaging to enhance drug screening processes.
  • Collaborated with Prof. Arno Kentgens on innovative research projects.

Postdoctoral fellow

Weizmann Institute of Science
Rehovot
2018.09 - 2022.03
  • Developed ultrafast 2D MQ/SQ correlation experiments to separate aromatic mixtures using hyperpolarization.
  • Implemented UF TOCSY techniques to enhance analysis efficiency in a single scan.
  • Designed a 1D MQ-filtered pulse sequence for J-coupling detection in insensitive nuclei.
  • Created UF P-Quantum experiments to detect multiple quanta efficiently within one scan.
  • Reduced dilution effects on hyperpolarization solution through innovative aqueous-organic solvent mixtures.
  • Generated radicals in samples via irradiation to minimise radical contamination and dilution.
  • Engineered rapid-melt DNP with dual-center magnet to minimise dilution and polarization losses.
  • Troubleshot DNP (Oxford Instruments) and NMR instrumentation effectively.

Graduate Research

ITMC, RWTH Aachen University
Aachen
2013.10 - 2018.03
  • Low-field NMR spectroscopy at 1 Tesla NMR for real-time reaction monitoring.
  • Studied reaction mechanisms various reactions, in real-time using compact NMR, such as of acetalization and transesterification for biofuel production.
  • Developed method to study kinetic isotope effect in real-time with compact NMR.
  • Explored compact NMR's potential for process control in polymer analysis.
  • Investigated compact NMR applications in structure elucidation of complex molecules.

Masters Research Project

Guru Nanak Dev University
Amritsar
2010.07 - 2011.06
  • Developed methodology for removing contaminated dyes from aqueous solutions using unconventional adsorbents.
  • Monitored performance of two adsorbents through ex-situ UV-Vis spectroscopy across varied concentrations and temperatures.
  • Conducted research on adsorption of Congo red dye employing banana peels and bagasse charcoal.

Education

Ph.D. - Chemistry

RWTH Aachen University
Aachen, Germany
2013.10 - 2018.03

M.Sc. - Honours Chemistry

Guru Nanak Dev University
Amritsar, India
2009.08 - 2012.07

B.Sc. - Honours Chemistry

Guru Nanak Dev University
Amritsar, India
2006.07 - 2009.06

Skills

  • Operation, optimisation, and troubleshooting of low- and high-field NMR spectrometers (Bruker, Magritek)
  • Small-molecule solution-state NMR: reaction monitoring, structure elucidation, and data interpretation
  • Advanced NMR methods (including ultrafast multidimensional and multiple-quantum experiments)
  • Dynamic Nuclear Polarization (DNP) operation and experimental support
  • NMR software: TopSpin, MestreNova (acquisition, processing, and analysis)
  • Cryogenic operations and magnet safety (fills, high-field environments)
  • User training and technical support for multi-user NMR facilities
  • Supervision and mentoring of PhD students and researchers
  • Teaching and training in NMR theory and practical courses (Master’s and PhD level)
  • Facility coordination and collaboration across academic and industrial research groups

REFERENCES

  • Clare, Grey, Prof., cpg27@cam.ac.uk, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge
  • Lucio, Frydman, Prof., lucio.frydman@weizmann.ac.il, Weizmann Institute of Science, Rehovot, Israel
  • Bernhard, Bluemich, Prof., bluemich@itmc.rwth-aachen.de, RWTH Aachen University, Aachen, Germany
  • Michael, De Volder, Prof., mfld2@cam.ac.uk, Institute for Manufacturing, University of Cambridge, Cambridge

AWARDS AND SCHOLARSHIPS

1. Magnetic Resonance in Chemistry (MRC) Award 10 July, 2025, Awarded by EUROMAR in Oulu for excellent contributions in magnetic resonance.

2. Marie-Curie postdoctoral research fellowship 01/01/2025-31/12/2026, Tracking real-time chemical evolutions in redox flow batteries using modern ultrafast 2D NMR and localized MRI techniques.

3. The Borchers Badge for Ph.D. thesis with ‘Distinction’ at RWTH Aachen University 17/10/2019, The Borchers Badge is awarded to RWTH Aachen doctoral candidates, who pass their doctoral examinations "With Distinction". The Borchers Badge is awarded in the form of a Badge of Honour. 

4. Feinberg Postdoc Fellowship, Weizmann Institute of Science 01/09/2018 - 31/05/2022, Feinberg Graduate school provides three year fellowship for pursuing research work.

5. SMASH NMR Conference award 20/09/2015 - 23/09/2015, SMASH conference offers ~20-30 scholarships to support participation by graduate students and attendees holding academic post-doctorate positions.

6. Experimental NMR Conference Travel Stipend 10/04/2015 - 15/04/2015, The ENC travel stipend award is given to approximately 50 graduate students and provides free conference registration as well a stipend to assist in covering travel costs. The award is funded by the ENC, the Suraj P. Manrao Science Foundation, and contributions from companies.

7. Aachen-California network exchange stipend 10/04/2015 - 15/04/2015, The Aachen California Network of Student and Staff Exchange, ACalNet for short, is a thematic network of the German Academic Exchange Service, DAAD, that promotes closer collaboration between RWTH Aachen and universities in California. The network is financed by the BMBF and offers students, doctoral candidates, and academic staff at the university the possibility to complete a research stay at a university abroad.

8. Junior Research fellowship, National eligibility test, India 23/11/2012, This fellowship is given to top percentage of students for a competitive eligibility test for pursuing doctorate in India for five years.

PEER-REVIEWED PUBLICATIONS

  • 1. K. Singh, L. Frydman, Single-Scan Heteronuclear 13C-15N J-Coupling NMR Observations Enhanced by Dissolution Dynamic Nuclear Polarization, J. Phys. Chem. Lett. 15 (2024) 5659.
  • 2. A. Giannoulis, K. Butbul, R. Carmieli, J. Kim, E. T. Montrazi, K. Singh, L. Frydman, Cryogenic and Dissolution DNP NMR on γ-Irradiated Organic Molecules, J. Am. Chem. Soc. 146 (2024) 20758-20769.
  • 3. B. Tickner, K. Singh, L. Frydman, V. V. Zhivonitko, V. Veikko Telkki, Ultrafast Nuclear Magnetic Resonance as a Tool to Detect Rapid Chemical Change in Solution, ACS Phys. Chem Au 4 (2024) 453-463.
  • 4. I. Katz, A. Feintuch, R. Carmieli, S. Markovic, K. Singh, T. Harris, L. Frydman, Dynamic nuclear polarization enhancement of 13C in glucose using electrical discharge induced radicals as polarizing agents, JMRO 10-11 (2022) 100043.
  • 5. K. Singh, C. Jacquemmoz, P. Giraudeau, L. Frydman, J-N. Dumez, Ultrafast 2D 1H-1H NMR spectroscopy of DNP-hyperpolarised substrates for the analysis of mixtures, Chem. Commun. 57 (2021) 8035-8038.
  • 6. K. Singh, S. P. Kumar, B. Bluemich, Monitoring the mechanism and kinetics of a transesterification reaction for the biodiesel production with low field 1H NMR spectroscopy, Fuel 243 (2019) 192-201.
  • 7. D. Weidener, K. Singh, B. Bluemich, Synthesis of α-Fluoro-α,β-unsaturated esters monitored by 1D and 2D benchtop NMR Spectroscopy, Magn. Reson. Chem. 57 (2019) 852-860.
  • 8. K. Singh, B. Bluemich, Online monitoring of the kinetic isotope effect in chemical reactions with 1H and 19F low-field NMR spectroscopy, Analyst 143 (2018) 4408-4421.
  • 9. B. Bluemich, K. Singh, Desktop NMR and its applications from materials science to organic chemistry, Angew. Chem. 57 (2018) 6996-7010.
  • 10. K. Singh, B. Bluemich, Compact low-field NMR spectroscopy and chemometrics: A tool box for quality control of raw rubber, Polymer 141 (2018) 154-165.
  • 11. K. Singh, B. Bluemich, Desktop NMR for structure elucidation and identification of strychnine adulteration, Analyst 142 (2017) 1459-1470.
  • 12. K. Singh, E. Danieli, B. Bluemich, Desktop NMR spectroscopy for real-time monitoring of an acetalization reaction in comparison with gas chromatography and NMR at 9.4 T, Anal. Bioanal. Chem. 409 (2017) 7223-7234.
  • 13. K. Singh, B. Bluemich, NMR spectroscopy with compact instruments, Trends Anal. Chem. 83 (2016) 12-26.
  • 14. K. Singh, B. Bluemich, Desktop NMR Spectroscopy for quality control, Macromol.Symp. 365 (2016) 191-193.
  • 15. K. Singh, B. Bluemich, Compact NMR spectroscopy with shift reagents, Appl. Magn. Reson. 47 (2016) 1135-1146.
  • 16. J. Perlo, K. Singh, J. Viess, E. Danieli, M. Kuppers, B. Bluemich, Magisch Magnetisch: Transportprozesse fur Energiespeicher, Medizin- und Verfahrenstechnik, RWTH-Themen 1 (2015) 46-50.
  • 17. D. Hey, K. Singh, E. Jónsson, C. P. Grey, An ex-situ NMR study of the electrochemical degradation of 2,6-dihydroxyanthraquinone (DHAQ) in a Redox Flow Battery, Electrochimica Acta (submitted).
  • 18. N. L. Farag, K. C. Mylrea, D. Hey, K. Singh, D. S. Wright, C. P. Grey, The Behaviour of Phenothiazines as Catholytes in Aqueous-Organic Redox Flow Batteries, Energy and environmental Science (submitted).

LEADERSHIP AND MENTORING

  • Greta Thomson Ph.D. Candidate, University of Cambridge 2023-2025
  • Nadia Farag Ph.D. Candidate, University of Cambridge 2023-2024
  • Dominic Hey Ph.D. Candidate, University of Cambridge 2023-2024
  • Dennis Weidner Ph.D. Candidate, University of Cambridge 01/08/2016 - 31/08/2017
  • Sharoff Pon Kumar Master Thesis student, RWTH Aachen University
  • Thesis title: Synthesis of α-Fluoro-α,β-unsaturated esters monitored by 1D and 2D benchtop NMR Spectroscopy 01/04/2017- 31/07/2017
  • Anne Nickel Bachelor Internship student, RWTH Aachen University.
  • Project title: Analytical methods to resolve spectral resolution at low-field NMR 01/06/2016 -31/10/2016
  • Anne Nickel Master Internship student, RWTH Aachen University.
  • Project title: Compact NMR spectroscopy with shift reagents and quality control

TEACHING EXPERIENCE

  • Supervised Part II Course C3, University of Cambridge. Easter term, 2023

     NMR spectroscopy of molecules and materials

  • Substitute lecturer, RWTH Aachen University, Aachen 01/09/2016 - 30/03/2017

     Several lectures for a postgraduate NMR course, namely NMR spectroscopy employing 1D and 2D      

     NMR experiments, were given.

  • Practical Teaching Assistant, RWTH Aachen University, Aachen 01/04/2014 - 30/10/2016

     Worked as teaching assistant in Praktikum Makromolekulare Chemie in Institute of macromolecular     

     chemistry laboratory for assisting undergraduate students in NMR, FT-IR, Viscometry, DSC.

  • Guest lecturer, Sarup Rani Government College, Amritsar 01/08/2012 - 30/03/2013

      For two semesters, The Researcher taught physical chemistry to third-year undergraduates, covering        spectroscopic methods such as UV-Vis, IR, and NMR spectroscopy, as well as physical chemistry.

  • Assistant Professor, Guru Nanak Dev University College, Amritsar 01/07/2011 - 31/03/2012

      For two semesters, The Researcher taught Physical chemistry to first-year undergraduates, covering     

      both Organic and Physical chemistry. Students in the 12th grade were taught general chemistry.

SERVICE TO PROFESSION – REVIEWER FOR JOURNAL

Applied magnetic resonance, Magnetic resonance in chemistry, Fuel, Talanta, Polymer, Analyst, Analytical Chemistry, Angewandte Chieme, ChemistrySelect and ChemistryOpen journals.

OUTREACH AND OTHER ACTIVITIES

  • 1. Participated in and taught chemistry experiments to the public, including children, during the Chemistry Open Days at the University of Cambridge for three consecutive years (2023–2025).
  • 2. Presented research work in Tag der Chemie for four years (2014–2018) at RWTH Aachen University. This Chemistry Day is the central celebratory event of the Chemistry Department. The departments present their current research to students, employees, doctoral candidates, and the interested public in numerous exciting lectures. In addition, career planning paths in science and industry are shown.
  • 3. Volunteered and organized a science exhibition (2012–2013) at Sarup Rani Government College, Amritsar, for introducing science to the public and students using models, charts, and real-life examples.

Timeline

Marie Sklodowska-Curie Actions – Postdoctoral Fellow (MSCA-PF)

University of Cambridge
2025.01 - Current

Postdoctoral Research Associate with Shell, Amsterdam

University of Cambridge
2023.02 - 2025.12

Postdoctoral fellow

Radboud University
2022.04 - 2023.01

Postdoctoral fellow

Weizmann Institute of Science
2018.09 - 2022.03

Graduate Research

ITMC, RWTH Aachen University
2013.10 - 2018.03

Ph.D. - Chemistry

RWTH Aachen University
2013.10 - 2018.03

Masters Research Project

Guru Nanak Dev University
2010.07 - 2011.06

M.Sc. - Honours Chemistry

Guru Nanak Dev University
2009.08 - 2012.07

B.Sc. - Honours Chemistry

Guru Nanak Dev University
2006.07 - 2009.06
Kawarpal Singh