JOSHUA EKUNDAYO

Title: The role of ADAR-mediated editing in Cancer

Outline:

Independently designed, conducted and composed an experimental research project investigating the epitranscriptomic ADAR enzymes and their role in immune modulation and cancer progression through their A-to-I RNA editing activity.

Specifically, the study aimed to determine whether carcinogenesis was associated with any changes with respect to ADAR gene expression and to elucidate which specific biological pathways with oncogenic potential were most closely associated with ADAR-edited transcripts.

Key Responsibilities:

• Employed a range of in vitro techniques including: HUVEC culturing, cell seeding, hemocytometer cell counting, TRIzol-based RNA isolation, cDNA synthesis, and quantitative RT-PCR.
• Applied gene ontology and pathway analysis (DAVID) to ADAR-associated dsRNA-transcripts to identify biological functions and potential pro-oncogenic interactions.
• Collated and expressed my findings in the form of a 5k word report, , integrating current knowledge in the field and outlining future perspectives to advance understanding.
  

• Directed and assisted large groups of festival-goers, ensuring smooth flow and preventing overcrowding in designated areas
• Monitored entry and exit points, managing the movement of people to maintain safety and order
• Worked collaboratively with a diverse team of stewards, security personnel, and event organizers to ensure the event ran smoothly

• Organised, developed and presented a project relating to the future of work under the 'Business Insights' program
• Consistently met my short and long-term targets
• Proactively participated in meetings alongside my peers and helped develop ideas.

• Welcomed patients, gathered medical histories, and updated patient records
• Assisted with patient education regarding dental procedures and post-care instructions
• Ensured patients' comfort and addressed any concerns or questions before and after treatments
• Handled and processed a range of medical documentation and organised information both electronically and physically.