Frederic H.S. Buemi
London,United Kingdom
Summary
PhD graduate with strong hands-on experience in LC–MS analysis and characterisation of biopharmaceuticals, including data processing, interpretation and quality assessment. Experienced with mass spectrometry techniques such as intact protein analysis, peptide mapping and DAR determination, alongside recombinant protein expression, purification and FRET-based activity assays. Motivated by collaborative, cross-functional work and by contributing to robust, high-throughput analytical workflows that support biopharmaceutical process and product development to deliver real-world impact.
Overview
6
6
years of professional experience
Work history
Research Fellow in High Throughput Screening
University of Surrey
Guildford, Surrey
03.2025 - Current
Industry collaboration with AstraZeneca (Cambridge, England) focused on identification and characterisation of inhibitors of ADAMTS8. This work involves expression and purification of enzyme, followed by FRET-based activity assays to support inhibitor screening and validation. In parallel, I perform LC- and MS-based analytical characterisation of biopharmaceutical candidates, as well as MS analyses such as intact protein analysis and peptide mapping. Strong emphasis on data quality, method robustness and documentation in industry-driven, high-throughput environments.
Laboratory and Clinical Apprentice
King Hamad University Hospital
Busaiteen, Kingdom of Bahrain
11.2019 - 03.2020
4-month work experience in one of the leading hospitals of the Middle East which allowed me to acquire first-hand practice and knowledge of the haematology department, from patient sample collection to analysis.
Education
Doctorate of Philosophy - Medical Research
Imperial College London
London, United Kingdom 10/2020 - 12/2024
Master of Science - Molecular Medicine
Imperial College London
London, United Kingdom 10/2018 - 07/2019
Bachelor of Science - Biomedical Science
Imperial College London
London, United Kingdom 10/2015 - 07/2018
GCE Advanced Level (A-Levels) - Mathematics, Biology, Chemistry and Physics
The British School of Bahrain
Hamala, Kingdom of Bahrain 09/2012 - 06/2014
Skills
- LC–MS analysis with data processing, interpretation and quality assessment
- Mass spectrometry: intact protein analysis, peptide mapping, DAR determination
- Recombinant protein expression & purification; FRET assays
- High-throughput, automation-ready workflows
- Cross-functional collaboration in biopharma environments
Accomplishments
Recipient of the Young Scientist and Best Speaker Award at the 2023 Proteinases and Inhibitors Conference (Tiers, Italy).
LANGUAGES
French
Native
English
Fluent
German
Intermediate
Affiliations
- Running
- Music
References
References available upon request.
Timeline
Research Fellow in High Throughput Screening
University of Surrey
03.2025 - Current
Laboratory and Clinical Apprentice
King Hamad University Hospital
11.2019 - 03.2020
Doctorate of Philosophy - Medical Research
Imperial College London
10/2020 - 12/2024
Master of Science - Molecular Medicine
Imperial College London
10/2018 - 07/2019
Bachelor of Science - Biomedical Science
Imperial College London
10/2015 - 07/2018
GCE Advanced Level (A-Levels) - Mathematics, Biology, Chemistry and Physics
The British School of Bahrain
09/2012 - 06/2014