Dr. Hannah Safi

Clinical Scientist and Biomedical Engineer with 9 years of experience supporting the development, evaluation, implementation, and optimisation of medical technologies across the NHS, industry, and academic healthcare environments. Experienced in working directly with healthcare professionals, providing technical support, user training, device evaluation, and troubleshooting to facilitate the safe and effective use of complex medical devices.

A collaborative and customer-focused professional with a proven track record of building strong relationships with clinicians, nurses, technicians, researchers, and industry stakeholders. Skilled in clinical education, stakeholder engagement, medical device regulation, quality assurance, and cross-functional project delivery. Committed to improving patient outcomes through the successful adoption of innovative healthcare technologies and evidence-based clinical solutions.

• The UK 2024 Academy for Healthcare Science Award (awarded alongside team) - Innovative Practice to Enhance Patient Safety
• Biotechnology and Biological Sciences Research Council, 2014 – PhD Studentship
• University of Portsmouth, 2014– Best BSc (Hons) final year research project
• University of Portsmouth, 2014– Best student of the year

• Clinical Scientist – The Health and Care Professions Council, registration number: CS022127
• Full Member – Institute of Physics and Engineering in Medicine

• Delgado-Sanchez A, Charalambous C, Safi H, Jones A, Brown C, Trujillo-Barreto NJ. EEG Correlates of the Influence of Somatosensory Input, Expectations and Trait-Like Bias on Pain Perception. Eur J Pain. 2025 Nov;29(10):e70154. doi: 10.1002/ejp.70154.
• Beyene, S., Tufaro, V., Garg, M., Gkargkoulas, F., Calderon, AT., Safi, H., Waksman, R., Windecker, S., Torii, R., Melaku, GD., Bulant, CA., Bourantas, CV., Blanco, PJ., Garcia-Garcia, HM. Comparison of endothelial shear stress between ultrathin strut bioresorbable polymer drug-eluting stent vs durable-polymer drug-eluting stent post-stent implantation: An optical coherence tomography substudy from BIOFLOW II. Cardiovascular Revascularization Medicine. 2024. doi.org/10.1016/j.carrev.2023.11.014.
• Delgado-Sanchez, A., Charalambous, C., Trujillo-Barreto, N.J., Safi, H., Jones, A., Sivan, M., Talmi, D., Brown, C. (2024). Test–retest reliability of Bayesian estimations of the effects of stimulation, prior information and individual traits on pain perception. European Journal of Pain. 2023. doi.org/10.1002/ejp.2193
• Beyene,S., Safi,H., Kuku, KO., Desale, S., Waksman, R., Torii, R., Bourantas, C., Garcia-Garcia, HM., Comparison of Shear Stress Related to Neointimal Healing Between Ultrathin, Bioresorbable-Polymer Sirolimus-Eluting Stents Versus Thin, Durable-Polymer Everolimus-Eluting Stents in Patients Undergoing Coronary Revascularization: An Optical Coherence Tomography BIOFLOW II Substudy. Cardiovascular Revascularization Medicine. 2022. doi.org/10.1016/j.carrev.2022.06.107.
• Bajaj R, Huang X, Kilic Y, Ramasamy A, Jain A, Ozkor M, Tufaro V, Safi H, Erdogan E, Serruys PW, Moon J, Pugliese F, Mathur A, Torii R, Baumbach A, Dijkstra J, Zhang Q, Bourantas CV. Advanced deep learning methodology for accurate, real-time segmentation of high-resolution intravascular ultrasound images. Intl J Cardiology 2021. doi.org/10.1016/j.ijcard.2021.06.030.
• Safi H, Tufaro V, Torii R, Ramasamy A, Mathur A, Jones DA, Lansky A, Konstantinou K, Little CD, Rakhit R, Karamasis GV, Baumbach A, Bourantas CV. Role of the local hemodynamic forces estimated in three dimensional quantitative coronary angiography (3D-QCA) models in predicting non-flow limiting coronary lesions that cause cardiovascular events: a retrospective observational multicentre study. Atherosclerosis 2021. doi.org/10.1016/j.atherosclerosis.2021.02.018.
• Jin CY, Ramasamy A, Bourantas CV, Safi H, Kilic Y, Tufaro V, Bajaj R, Jones D; Mathur A, Baumbach A. Diagnostic accuracy of Quantitative Flow Ratio (QFR) and Vessel Fractional Flow Reserve (vFFR) compared to Fractional Flow Reserve (FFR) based on 7.5 frames/second and 7 pulse/second coronary angiography. Int J Cardiovasc Imaging. 2021. doi.org/10.1007/s10554-020-02133-8.
• Ramasamy A, Jin CY, Tufaro V, Bajaj R, Kilic Y, Safi H, Amersey R, Jones D, Torii R, Lansky A, Mathur A, Bourantas CV, Baumbach A. Computerised Methodologies for Non-Invasive Angiography-Derived Fractional Flow Reserve Assessment: A Critical Review. J Int Cardio 2020. doi.org/10.1155/2020/6381637.
• Kilic Y, Safi H, Bajaj R, Serruys PW, Kitslaar P, Ramasamy A, Tufaro V, Onuma Y, Mathur A, Torii R, Baumbach A, Bourantas CV. The evolution of data fusion methodologies developed to reconstruct coronary artery geometry from intravascular imaging and coronary angiography data: a comprehensive review. Front. Cardiovasc. Med. 7:33. doi.org/10.3389/fcvm.2020.00033.
• Safi H, Bourantas CV, Ramasamy A, Zanchin T, Bär S, Tufaro V, Jin CY, Torii R, Karagiannis A, Reiber JHC, Mathur A, Windecker S, Lansky A, Maehara A, Serruys PW, Stone P, Baumbach A, Stone G, Räber L. Predictive value of the QFR in detecting vulnerable plaques in non-flow limiting lesions: a combined analysis of the PROSPECT and IBIS 4 study. Int J Cardiovasc Imaging. 2020. doi: 10.1007/s10554-020-01805-9.
• Bourantas CV, Zanchin T, Torii R, Serruys PW, Karagiannis A, Ramasamy A, Safi H, Coskun AU, Koning G, Onuma Y, Zanchin C, Krams R, Mathur A, Baumbach A, Mintz G, Windecker S, Lansky A, Maehara A, Stone PH, Raber L, GW Stone. Predictive value of the shear stress distribution estimated in three dimensional quantitative coronary angiography models in detecting vulnerable plaques: a combined analyss of the PROSPECT and IBIS 4 study. J Am Coll Cardiol Img. 2020. doi: 10.1016/j.jcmg.2020.02.028
• Ramasamy A, Safi H, Moon JC, Andiapen M, Rathod KS, Maurovich-Horvat P, Serruys PW, Mathur A, Baumbach A, Pugliese F, Torii R, Bourantas CV. Evaluation of the efficacy of computed tomographic coronary angiography in assessing coronary artery morphology and physiology: rationale and study design. Cardiology 2020. doi: 10.1159/000506537.
• Davis AT, Safi H, Maddison SM. The reduction of dose in paediatric panoramic radiography: the impact of collimator height and programme selection. Dentomaxillofac Radiol 2015. doi: 10.1259/dmfr.20140223.

• Swift C, Safi H, Liang S. Evaluating the hazards and management of equipment emitting artificial optical radiation in the healthcare sector. (2026, June). Oral Presentation given at the 7th European IRPA Congress, Liverpool, UK.
• Safi H, Parkin D, Liang S, Allan D, Watson S. Photoprotection against Visible Light using New Formulation Sunscreen Products. (2022, October). Oral Presentation given at the Optical Radiation Update Meeting, Birmingham, UK.
• Liang S, Safi H, Samraj P, Allan D, Watson S. MedPen – An LED Based MED Tester. (2022, October). Oral Presentation given at the Optical Radiation Update Meeting, Birmingham, UK.
• Safi H, Bourantas CV, Ramasamy A, Tufaro V, Torii R, Reiber JHC, Mathur A, Onuma Y, Maehara A, Serruys PW, Stone P, Baumbach A, Stone G, Räber L. Predictive value of the quantitative flow ratio in detecting vulnerable plaques in non-flow limiting lesions: a combined analysis of the PROSPECT and IBIS 4 studies. (2020, May). Poster Presentation accepted for EuroPCR, Paris, France.
• Tufaro V, Safi H, Torii R, Mathur A, Konstantinou K, Little C, Rakhit R, Karamasis G, Baumbach A, Bourantas CV. Role of the local hemodynamic forces estimated in three dimensional quantitative coronary angiography (3D-QCA)-derived models in predicting non-flow limiting coronary lesions that cause cardiovascular events: a retrospective observational multicentre study (2020, May). Oral Presentation accepted for EuroPCR, Paris, France.
• Tufaro V, Safi H, Torii R, Mathur A, Konstantinou K, Little C, Rakhit R, Karamasis G, Baumbach A, Bourantas CV. Role of the local hemodynamic forces estimated in three dimensional quantitative coronary angiography (3D-QCA)-derived models in predicting non-flow limiting coronary lesions that cause cardiovascular events: a retrospective observational multicentre study (2020, April). the 14th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, Rotterdam, Netherlands.
• Jin CY, Ramasamy A, Bourantas CV, Safi H, Kilic Y, Tufaro V, Bajaj R, Jones DA, Mathur A, Baumbach A. Diagnostic accuracy of Quantitative Flow Ratio (QFR) and Vessel Fractional Flow Reserve (vFFR) compared to Fractional Flow Reserve (FFR) based on 7.5 frames/second coronary angiography. (2019, August). Poster Presentation given at the European Society of Cardiology congress, Paris, France.
• Ramasamy A, Jin CY, Safi H, Zanchin T, Jones D, Kitslaar P, Dijkstra J, Onuma Y, Raber L, Ozkor M, Krams R, Mathur A, Serruys PW, Baumbach A, Bourantas CV, Torii R. A novel methodology for accurate reconstruction and assessment of the local hemodynamic forces in metallic stented coronary artery segments. (2019, May). Poster Presentation given at EuroPCR, Paris, France.
• Torii R, Ramasamy A, Jin CY, Safi H, Zanchin T, Jones D, Kitslaar P, Dijkstra J, Onuma Y, Raber L, Ozkor M, Krams R, Mathur A, Serruys PW, Baumbach A, Bourantas CV. A novel method for more representative vessel model reconstruction and assessment of the local hemodynamic forces in coronary artery segments with metallic stent. (2019, April). Poster Presentation given at the 14th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, London, UK.
• Safi H, Phillips N, Bomphrey R.J., Ventikos, Y. Experimentally Validated Fluid-Structure Interaction Abdominal Aortic Aneurysm Models. (2018, July). Poster Presentation given at the 8th World Congress of Biomechanics, Dublin, UK.
• Safi H, Phillips N, Bomphrey R.J., Ventikos, Y. Implementing Fluid-Structure Interaction Computational and Empirical Techniques to Assess Hemodynamics of Abdominal Aortic Aneurysms. (2017, October). Oral Presentation given at the annual meeting of the Association for Research into Arterial Structure and Physiology, Pisa, Italy.
• Safi H, Phillips N, Bomphrey R.J., Ventikos, Y. Fluid-structure interactions in abdominal aortic aneurysms: validating computational models. (2017, September). Oral Presentation given at the ECCOMAS Thematic Conference on Multiscale Problems in Biomechanics and Mechanobiology, Vienna, Austria.
• Safi H, Phillips N, Bomphrey R.J. Blood Flow and the Development of Aneurysms: Novel Investigative Measurements. (2016, July). Oral Presentation given at the annual meeting of the Society for Experimental Biology, Brighton, UK.
• Phillips N, Safi H, Michaelis D, Nagel H, Bomphrey R. Towards a Fluid-Structure Interaction measurement technique for the biosciences: combined measurements of fluid flow and tube wall deformation associated with a simplified aneurysm. (2015, January). Poster session presented at the annual meeting of the Society for Integrative and Comparative Biology, Florida, USA.