Dashneet Kaur

Detail-oriented and highly motivated MSc Biotechnology student with extensive hands-on laboratory experience and a strong foundation in molecular biology, biochemistry, and genetic engineering. Proficient in advanced RNA sequencing, Hi-C techniques, cancer research methodologies, quantitative PCR, and chromatography. Demonstrated ability to conduct complex experiments, analyze data, and contribute to innovative research projects. Possess excellent technical writing, data analysis, and laboratory safety skills. Seeking an entry-level position in a dynamic biotech environment where I can apply my knowledge and skills to contribute to cutting-edge scientific advancements.

Title: Integrative Analysis of Chromatin Architecture and Transcriptomics in Human Cancers

Nottingham Trent University, Nottingham, United Kingdom

• Objective: Investigated the 3D genome organization in cancer cells by integrating Hi-C and transcriptomics data to identify structural variations and gene expression changes.
• Techniques Used: Hi-C, RNA sequencing, data integration, bioinformatics tools (e.g., HiC-Pro, DESeq2, GEO), and statistical analysis.
• Key Responsibilities:Designed and executed Hi-C and RNA-seq experiments to collect comprehensive genomic and transcriptomic data.
  Analyzed Hi-C data to map chromatin interactions and identify significant structural variations.
  Performed differential gene expression analysis using RNA-seq data and GEO tools to identify cancer-specific transcriptomic changes.
  Integrated Hi-C and transcriptomics data to correlate chromatin structure alterations with gene expression profiles.
  Collaborated with a multidisciplinary team to interpret results and prepare detailed reports.