Antonella Calandriello

Reporting to the Global Medical Project Director, managing and leading the European Field Medical Affairs team of MSLs in support of clinical development and future product launches in oncology: RCR, CRC, SCHNC, and NETs.

Ensuring the effectiveness of the team providing guidance and support to the MSLs, leading by example, promoting, and fostering effective communication, a collaborative, inclusive, and healthy work environment.

Field Medical Strategy.

Congress Coordination and Participation

KOLs management.

Field Medical Lead Team Support and Development

Development of Cancer Vaccines

Reporting to VP Medical Affair & Clinical Development, Headquarter USA

Liaising between Company and KOLs for Therapeutic areas of interest in Europe: Melanoma H&N, NSCLC

Managing and maintaining relationships with key strategic and thought leaders/KOLs in Europe

Support to Clinical Development, Sponsor Trials and IITS; Development of EU Medical Affair Plan and Supporting activities for Publication Plan

Congresses Participation and Congress Lead for EU: Meetings plan, Pre and Post Congress Reporting

Field Activities: Support identifying Medical Education opportunities for IO Biotech, support for Enrollment in ongoing trials, creation of tools for insights reporting of Field medical, Supporting Clinical Development for Insight collections related to Pipeline, Support Clinical Ops con Site Engagement and Communication Style

Coordinating activities for hiring and onboarding new MSLs team in US and EU Developing training roadmap and material for new hired MSLs; coordinating all training activities for new hired MSLs for therapeutic area of interest; updating proactive/reactive materials for MSL to use on field; coordinating MSLs activities and communication strategy in the field

Gathering and Organizing Insights' collection for New Product Launch

Development and lunch of Zandelisib, a new generation PI3K inhibitor in hemato-oncology and solid tumors, plus early compounds in the pipeline.

Liaise between the company and KOLs for therapeutic areas of interest in Europe.

Reporting to VP Medical Affair Headquarter USA and closely collaborating with VP Clinical Development

Support Clinical Development gathering insights for Strategic Development of product in Pipeline (B-cell and T-cell Malignancy, AML and Solid Tumors)

Support the development of the Medical Affairs Plan for the USA and create the Medical Affairs Plan for the EU according to the company's business strategy.

Active support in launch activities for Zandelisib in the US: collaborating for KOLs insights consolidation and engagement strategy.

Support sponsored trials by providing input on potential PIs, assisting the clinical operations team where appropriate and needed for scientific communications, recruiting PIs, referring to and engaging KOLs for trial participation, attending SIVs in designated regions, and reaching out to or meeting with PIs at open sites.

Collecting insights for the improvement of current protocols and new amendments.

European Lead for Investigator-Initiated Trials: collecting proposals, supporting start-up activities, and managing the process of clinical trial activation, liaising between internal teams and the Sponsor Institution.

Support Congresses in US and Europe: Leading Activities EHA 2020, 2021, 2022; AACR 2020; Lead for ASH 2020, 6-ICM, ASCO 2021, providing summary reports and highlights.

Managing and maintaining relationships with key strategic and thought leaders, KOLs, in Europe.

Field activities support identifying medical education opportunities for MEI Pharma, contributing to slide deck creation and updates for field use, and leading the development of tools to improve product-related communications in the field.

Management of the advisory board and steering committee meeting: identifying and/or engaging international experts; board preparation, participation, and reporting for Medical Affairs.

Training and Support for the MSL team: developing a training roadmap and materials for newly hired MSLs; coordinating all training activities for newly hired MSLs in the therapeutic area of interest; updating proactive/reactive materials for MSL use in the field; coordinating MSL activities and communication strategies in the field.

Liaise between Company and KOLs for Therapeutic areas of interest

Provide appropriate field medical affairs support in line with the local medical plan and MSD culture.

Managing and maintaining relationships with key strategic and thought leaders/KOLs

Improve and update scientific documents necessary for providing medical support and answering queries internally and from external customers.

Preparing scientific presentations, and participating in medical congresses for therapeutic areas of interest.

Keep up to date with clinical knowledge, published data, and trial work for MSD and competitive product studies.

Develop strong communication links with KOLs, study physicians, and their teams to engage in peer-to-peer scientific exchange regarding disease, clinical unmet needs, and clinical trials.

Support of ongoing and future company-sponsored trials.

Collaborate with physicians on medical affairs initiatives, such as advisory boards, hospital meetings, medical education opportunities, and trainings, and support physicians in the ISS submission process.

Participation and support lunch activities for Pembrolizumab's new indication in lung and GI.

Active collaboration with Market Access for pre-launch activities during internal meetings, and providing scientific support in external meetings with stakeholders.

Field Force: Scientific Training for Communication in the Field.

Provide accurate and non-promotional scientific information relating to the scientific rationale and study criteria of Pharmacyclics-sponsored studies to specific study sites.

Keep up to date with clinical knowledge, published data, and trial work for Pharmacyclics and competitive product studies.

Support relevant education at Site Investigator Meetings (SIMs) in line with clinical study plans (as requested).

Develop strong communication links with KOLs, Study Physicians and their teams to engage in peer-to-peer scientific exchange regarding disease, clinical unmet needs & clinical trials

Act as field-based reference point of scientific and clinical expertise for study sites

Support of ongoing and future company-sponsored trials.

Support Pharmacyclics' presence in selected European congresses in alignment with the Pharmacyclics clinical development strategy (e.g.,

Staffing of clinical development/non-promotional booths at medical congresses.

Respond to requests for investigator-sponsored research in line with company procedures.

Build and promote the image and professionalism of Pharmacyclics in Europe.

Ensure compliance with SOPs (Standard Operating Procedures), GCP (Good Clinical Practice), and other relevant guidelines/processes on an ongoing basis.

Lead activities for CLL and MCL projects.

MSL on-the-job training and field support for newly hired MSLs.

Regional Medical Liaisons for the Enbrel Project, allocated on Immunology/Inflammatory Therapeutic Area, reporting to Local Medical Director for Italy and Portugal, liaising between national Medical Affairs (IT and PT), International Study Team, Clinical Operations and Development.

Provide appropriate field medical affairs support in line with the local medical plan and Amgen culture.

Managing and maintaining relationships with key strategic and International Thought Leaders/KOLs

Providing support during Clinical Trials conduction, improving recruitment, enrollment and retention of subjects

Improvement and updating of scientific documents necessary for provide medical support and answering queries internally and from external customers

Participation to Investigators Meetings improving relationship with Clinical Site representative, promoting a deeper understanding of Trial Protocol and high focus on study goals

Preparing scientific presentations, participate to medical congresses for therapeutic area of interest

Working in International Clinical Operations and Site Level and Management Level supporting Clinical Trials from PhI to PhIII in Oncology being involved in the development of Rituximab, Trastuzumab e Bevacizumab

Support and management on clinical trials in international teams supporting clinical trials PhII and PhIII in immunology, developing Adalimumab, in virology, Hepatitis C project and oncology with PARPi

Phytotherapic and Herbal dietary supplements and cosmetics company

Checking scientific literature for rational development of new herbal products and medical devices using payment databases

Medical writing, improvement and updating of scientific documents necessary for scientific support to Marketing, FF training, and to provide medical information answering queries internally and from external customers

Liaise between Company and KOL for Therapeutic areas of interest

Create and deliver strategic territory plans to provide appropriate field medical affairs support in line with local medical plan

Collaboration in Clinical Trials planning and implementation for new products and medical devices

Participation in the development and marketing of highly successful products: ImmunoMix Plus, Natura Mix, Adiprox, BioEulen

Therapeutic Areas and Disease: Immunomodulation, Metabolic Syndrome, Derma; Oncology

Department of Pharmaceutical Chemistry and Technology.

Research Activity: Development of new Organocatalyzed reactions using Selenium Chemistry

Department of Chemistry and Technology of Drugs.

Research Activity for Experimental Thesis: "Stereoselective synthesis of cyclopropanes containing quaternary stereocentres via organocatalytic Michael Addition to Vinyl Selenones": Synthesis of functionalized, enantiomerically pure cyclopropanes with potential therapeutic applications in central nervous system disorders (emotional and behavioral disorders).